HomePetros Kattou ENBrain stimulation for polymyositis safe and effective

Brain stimulation for polymyositis safe and effective


Are there any scientific studies using brain stimulation in Polymyositis Rheumatica?

a patient with cancer develops polymyositis at the same time. We don’t necessarily want to give the “standard drug” prednisolone because of the cancer, so I looked for studies to see whether we could treat this disease using our “modern” brain stimulation (vagal stimulator or tDCS).


why can brain stimulation possibly improve rheumatic = inflammatory diseases?

I will soon be writing a new post here about the reduction of cytokines such as TNF-Alpha, IL-3/6/9 and INF-y through brain stimulation

This shows in studies positiv effects on the body: be it Arthrosis pain, Arthritis, Intestinal inflammation, irritable bowel syndrome, Liver inflammation,……


Petros shows us numerous FMS / Pain patients

I can’t even think of incorporating his many testimonials (which he sends almost daily via WhatsApp) here in my homepage.

Plus: we have similar cases but my “Austrian” patients all tell me: “Video no, I don’t want to appear in public”, the Greeks don’t care or are happy if they do can help with giving a testimonial about the treatment that finally helped them after often years of suffering!


so our question is: can brain stimulation also treat a rheumatic (autoimmune?) disease such as Polymyositis?


Studies for polymyositis and brain stimulation

I actually found a positive study that answered this question with a definite YES

Summary: Helps with pain, has no side effects

Abstract of the study translated

new study from 2021 – Abstract translated and summarized

In one study, patients with myositis (an inflammation of the muscles) were divided into two groups: one group received active transcranial direct current stimulation (tDCS), while the other received sham tDCS treatment. Both groups showed comparable demographics, myositis types, disease duration, and disease status.

Results showed that after treatments:

Both groups showed improvements in pain intensity (as measured by the patient’s VAS score) and serum creatine phosphokinase levels, indicating a reduction in muscle inflammation.
– In the active tDCS group, there were additional improvements in physical aspects (measured with the SF-36 questionnaire) and lower limb muscle strength.

There were no significant differences between groups in anxiety (STAI), depression (BDI), or mobility (TUG). All patients fully adhered to the treatment protocoland there were no adverse events or disease relapses


The study shows that tDCS is safe and may potentially improve rehabilitation for myositis. However, further research with more participants and longer treatment periods is needed to confirm these results.



2020 study in dermatomyositis

Summary: helped and no side effects

Content of the study

actually a ridiculously small case report of 3 patients, one of whom was treated with tDCS and got better after only 3 treatments, while the 2 control patients – who only received placebo therapy – didn’t get any better.

Crucial: no side effects

Study 2020 from Sao Paolo



(c) Midjourney KI


Case report of dermatomyositis – long-term untreatable pain after shingles resolved in a very short time with brain stimulation

Summary: The patient was tormented for years by severe post-herpetic herpetic pain (shingles), which was massively improved in a very short time with brain stimulation, no side effects.

entire study summarized

by ChatGPT

Title: Transcranial Direct Current Stimulation Is Safe and Relieves Post-Herpetic Neuralgia in Patient with Dermatomyositis: A Case Report</strong > (2022)

  • Background: This case report describes the use of transcranial direct current stimulation (tDCS) in a patient with dermatomyositis who suffered from refractory postherpetic neuralgia. It is emphasized that tDCS is safe and does not lead to disease relapse.
  • Patient: The 49-year-old white woman has been treated for dermatomyositis since 2016. She received various therapies including methylprednisolone, immunoglobulin, immunosuppressants, and immunobiologics. In 2019, she developed a herpes zoster infection and subsequently post-herpetic neuralgia, which persisted despite treatment with gabapentin, duloxetine and pregabalin.
  • TDCS treatment: Due to inadequate pain control with medications, the patient underwent five daily tDCS sessions with a current of 2 mA for 20 minutes for five consecutive days. The electrodes were positioned according to the 10/20 International EEG system.
  • Concomitant exercises: During the tDCS sessions, the patient performed systematic exercises, including aerobics and resistance training.
  • Results: The disease was assessed using various scales and tests. A reduction in pain and its variants was noted. The patient reported no differences in her physical activity and did not perform a structured exercise program after the intervention.
  • Discussion: The report highlights the safety and effectiveness of tDCS in the treatment of postherpetic neuralgia in a patient with dermatomyositis and suggests that further studies are needed to confirm these results.< /li>


We have experienced several such difficult pain cases in our practice in the last 3 months!

(c) Midjourney KI


The study situation in the pubmed is not big but serious enough and positive that we can assume that brain stimulation with no side effects could reduce pain in his Polymyositis, so that we can save on cortisone, which we don’t necessarily want to give him because of his cancer!