We have been using LDN in our practice since 2011, at that time primarily for cancer patients and for multiple sclerosis. It is effective for every form of autoimmune disease by modulating the immune system toward “optimization” because it increases enkephalin/endorphin levels.
With ME/CFS patients, you have to start with ultra-low doses
We usually start with 0.1 mg – always in the morning, because ME/CFS patients somehow go berserk after 9 p.m. with the usual evening dose. Then we increase it until the first side effects occur, then reduce the dosage slightly.
Anyone without a doctor can get instructions and a prescription from me (Revers must be signed). Since most ME/CFS patients are immobile, it’s sufficient for a relative to show up with the patient’s findings and the signed revers.
I’m fully booked for many months, but it’s always sufficient to quickly write a prescription if I don’t have to answer any other questions.
Now, a new study has been published in May 2025 that demonstrates the mechanism of action and confirms the effect. Here is a simplified summary of the scientific article on low-dose naltrexone (LDN) and its effect on long COVID:
LDN may help with long COVID: New hope from a small dose of an old drug
Low-dose naltrexone restores TRPM3 ion channel function in natural killer cells from long COVID patients | Etianne Martini Sasso et al. | Frontiersin. Mol. Biosci., May 19, 2025, Volume 12 – 2025 | https://doi.org/10.3389/fmolb.2025.1582967
It’s completely crazy to treat CFS without LDN!
I even take LDN myself – simply for optimization, “Happy live – happy live.”
I wrote a similar article a few months ago:
And don’t forget the chronic, long-term treatment of the viruses. None of that helps much – but IT HELPS!!!
about LDN
Back then, we were the first in Europe to bring LDN into the spotlight.
At that time, doctors in the US who worked with it were threatened with having their licenses revoked.
I’ve experienced “miracles” with it time and again. At lectures on LDN, I say, “It may sound boastful, but it feels true: Since LDN, our cancer patients no longer die.”
The difference was so clear compared to the “pre-LDN era.” Here is my first article on LDN back then.
Here is the link to the Autotranslation via Google of this first Collection of LDN-Datas from 2011
https://ganzemedizin-at.translate.goog/ldn/?_x_tr_sl=de&_x_tr_tl=en&_x_tr_hl=de&_x_tr_pto=wapp
I’ve written about 30 articles about LDN.
The most impressive one – and I would also recommend it to colleagues – is the approximately 1.5-hour interview with one of the first users, Dr. Bihari – then Minister of Health in New York, who successfully treated hundreds of cancer, AIDS, and MS patients with it. I’ve included the video in the following article. linked in
here the Google english translation of my website back then, the important video of Dr. Bihari is anyways in English
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